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Overexpression and Knockdown of Hypoxia-Inducible Factor 1 Disrupt the Expression of Steroidogenic Enzyme Genes and Early Embryonic Development in Zebrafish
Hypoxia is an important environmental stressor leading to endocrine disruption and reproductive impairment in fish. Although the hypoxia-inducible factor 1 (HIF-1) is known to regulate the transcription of various genes mediating oxygen homeostasis, its role in modulating steroidogenesis-related gen...
Autores principales: | Tan, Tianfeng, Yu, Richard Man Kit, Wu, Rudolf Shiu Sun, Kong, Richard Yuen Chong |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
SAGE Publications
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5467919/ https://www.ncbi.nlm.nih.gov/pubmed/28634424 http://dx.doi.org/10.1177/1177625017713193 |
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