Lack of elevation in plasma levels of pro-inflammatory cytokines in common rodent models of pulmonary arterial hypertension: questions of construct validity for human patients

Translational research depends on the relevance of animal models and how well they replicate human disease. Here, we investigated plasma levels of three important pro-inflammatory cytokines (TNFα, IL-6, and MCP-1), known to be elevated in human pulmonary arterial hypertension (PAH), and systematical...

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Detalles Bibliográficos
Autores principales: Schlosser, Kenny, Taha, Mohamad, Deng, Yupu, Jiang, Baohua, McIntyre, Lauralyn A, Mei, Shirley HJ, Stewart, Duncan J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2017
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5467939/
https://www.ncbi.nlm.nih.gov/pubmed/28597756
http://dx.doi.org/10.1177/2045893217705878

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5467939/
https://www.ncbi.nlm.nih.gov/pubmed/28597756
http://dx.doi.org/10.1177/2045893217705878

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