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Mesothelial‐to‐mesenchymal transition as a possible therapeutic target in peritoneal metastasis of ovarian cancer

Peritoneal dissemination is the primary metastatic route of ovarian cancer (OvCa), and is often accompanied by the accumulation of ascitic fluid. The peritoneal cavity is lined by mesothelial cells (MCs), which can be converted into carcinoma‐associated fibroblasts (CAFs) through mesothelial‐to‐mese...

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Detalles Bibliográficos
Autores principales: Rynne‐Vidal, Angela, Au‐Yeung, Chi Lam, Jiménez‐Heffernan, José A, Pérez‐Lozano, María Luisa, Cremades‐Jimeno, Lucía, Bárcena, Carmen, Cristóbal‐García, Ignacio, Fernández‐Chacón, Concepción, Yeung, Tsz Lun, Mok, Samuel C, Sandoval, Pilar, López‐Cabrera, Manuel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons, Ltd 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5468005/
https://www.ncbi.nlm.nih.gov/pubmed/28247413
http://dx.doi.org/10.1002/path.4889