Activation of the same mGluR5 receptors in the amygdala causes divergent effects on specific versus indiscriminate fear

Although mGluR5-antagonists prevent fear and anxiety, little is known about how the same receptor in the amygdala gives rise to both. Combining in vitro and in vivo activation of mGluR5 in rats, we identify specific changes in intrinsic excitability and synaptic plasticity in basolateral amygdala ne...

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Detalles Bibliográficos
Autores principales: Rahman, Mohammed Mostafizur, Kedia, Sonal, Fernandes, Giselle, Chattarji, Sumantra
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2017
Materias:
Neuroscience
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5468087/
https://www.ncbi.nlm.nih.gov/pubmed/28555566
http://dx.doi.org/10.7554/eLife.25665

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5468087/
https://www.ncbi.nlm.nih.gov/pubmed/28555566
http://dx.doi.org/10.7554/eLife.25665

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