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A widespread family of serine/threonine protein phosphatases shares a common regulatory switch with proteasomal proteases
PP2C phosphatases control biological processes including stress responses, development, and cell division in all kingdoms of life. Diverse regulatory domains adapt PP2C phosphatases to specific functions, but how these domains control phosphatase activity was unknown. We present structures represent...
Autores principales: | Bradshaw, Niels, Levdikov, Vladimir M, Zimanyi, Christina M, Gaudet, Rachelle, Wilkinson, Anthony J, Losick, Richard |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
eLife Sciences Publications, Ltd
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5468089/ https://www.ncbi.nlm.nih.gov/pubmed/28527238 http://dx.doi.org/10.7554/eLife.26111 |
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