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Development of a selective agonist for relaxin family peptide receptor 3

Relaxin family peptides perform a variety of biological functions by activating four G protein-coupled receptors, namely RXFP1–4. Among these receptors, RXFP3 lacks a specific natural or synthetic agonist at present. A previously designed chimeric R3/I5 peptide, consisting of the B-chain of relaxin-...

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Detalles Bibliográficos
Autores principales: Wei, Dian, Hu, Meng-Jun, Shao, Xiao-Xia, Wang, Jia-Hui, Nie, Wei-Han, Liu, Ya-Li, Xu, Zeng-Guang, Guo, Zhan-Yun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5468247/
https://www.ncbi.nlm.nih.gov/pubmed/28607363
http://dx.doi.org/10.1038/s41598-017-03465-7