Two-step ATP-driven opening of cohesin head

The cohesin ring is a protein complex composed of four core subunits: Smc1A, Smc3, Rad21 and Stag1/2. It is involved in chromosome segregation, DNA repair, chromatin organization and transcription regulation. Opening of the ring occurs at the “head” structure, formed of the ATPase domains of Smc1A a...

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Detalles Bibliográficos
Autores principales: Marcos-Alcalde, Íñigo, Mendieta-Moreno, Jesús I., Puisac, Beatriz, Gil-Rodríguez, María Concepción, Hernández-Marcos, María, Soler-Polo, Diego, Ramos, Feliciano J., Ortega, José, Pié, Juan, Mendieta, Jesús, Gómez-Puertas, Paulino
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5468275/
https://www.ncbi.nlm.nih.gov/pubmed/28607419
http://dx.doi.org/10.1038/s41598-017-03118-9

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5468275/
https://www.ncbi.nlm.nih.gov/pubmed/28607419
http://dx.doi.org/10.1038/s41598-017-03118-9

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