Recombinant Thrombomodulin Exerts Anti-autophagic Action in Endothelial Cells and Provides Anti-atherosclerosis Effect in Apolipoprotein E Deficient Mice

Stress-induced alteration in endothelial cells (ECs) integrity precedes the development of atherosclerosis. Previous studies showed that the soluble recombinant thrombomodulin (rTM) not only increases ECs proliferation but also exerts anti-apoptotic activity in ECs. However, the functional significa...

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Detalles Bibliográficos
Autores principales: Chen, Po-Sheng, Wang, Kuan-Chieh, Chao, Ting-Hsing, Chung, Hsing-Chun, Tseng, Shi-Ya, Luo, Chawn-Yau, Shi, Guey-Yueh, Wu, Hua-Lin, Li, Yi-Heng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5468323/
https://www.ncbi.nlm.nih.gov/pubmed/28607460
http://dx.doi.org/10.1038/s41598-017-03443-z

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5468323/
https://www.ncbi.nlm.nih.gov/pubmed/28607460
http://dx.doi.org/10.1038/s41598-017-03443-z

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