A Poly(Lactic-co-Glycolic) Acid Nanovaccine Based on Chimeric Peptides from Different Leishmania infantum Proteins Induces Dendritic Cells Maturation and Promotes Peptide-Specific IFNγ-Producing CD8(+) T Cells Essential for the Protection against Experimental Visceral Leishmaniasis

Visceral leishmaniasis, caused by Leishmania (L.) donovani and L. infantum protozoan parasites, can provoke overwhelming and protracted epidemics, with high case-fatality rates. An effective vaccine against the disease must rely on the generation of a strong and long-lasting T cell immunity, mediate...

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Detalles Bibliográficos
Autores principales: Athanasiou, Evita, Agallou, Maria, Tastsoglou, Spyros, Kammona, Olga, Hatzigeorgiou, Artemis, Kiparissides, Costas, Karagouni, Evdokia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2017
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5468442/
https://www.ncbi.nlm.nih.gov/pubmed/28659922
http://dx.doi.org/10.3389/fimmu.2017.00684

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5468442/
https://www.ncbi.nlm.nih.gov/pubmed/28659922
http://dx.doi.org/10.3389/fimmu.2017.00684

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