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Mutations in the SH1 helix alter the thermal properties of myosin II

The myosin II SH1 helix is a joint that links the converter subdomain to the rest of the myosin motor domain and possibly plays a key role in the arrangement of the converter/lever arm. Several point mutations within the SH1 helix in human myosin IIs have been shown to cause diseases. To reveal whet...

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Detalles Bibliográficos
Autores principales: Shibata, Kotomi, Koyama, Tsubasa, Inde, Shohei, Iwai, Sosuke, Chaen, Shigeru
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Biophysical Society of Japan (BSJ) 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5468464/
https://www.ncbi.nlm.nih.gov/pubmed/28630813
http://dx.doi.org/10.2142/biophysico.14.0_67