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A loss of Pdxk model of Parkinson disease in Drosophila can be suppressed by Buffy

BACKGROUND: The identification of a DNA variant in pyridoxal kinase (Pdxk) associated with increased risk to Parkinson disease (PD) gene led us to study the inhibition of this gene in the Dopa decarboxylase (Ddc)-expressing neurons of the well-studied model organism Drosophila melanogaster. The mult...

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Detalles Bibliográficos
Autores principales: M’Angale, P. Githure, Staveley, Brian E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5468966/
https://www.ncbi.nlm.nih.gov/pubmed/28606139
http://dx.doi.org/10.1186/s13104-017-2526-8