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The human RNA-binding protein RBFA promotes the maturation of the mitochondrial ribosome

Accurate assembly and maturation of human mitochondrial ribosomes is essential for synthesis of the 13 polypeptides encoded by the mitochondrial genome. This process requires the correct integration of 80 proteins, 1 mt (mitochondrial)-tRNA and 2 mt-rRNA species, the latter being post-transcriptiona...

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Detalles Bibliográficos
Autores principales: Rozanska, Agata, Richter-Dennerlein, Ricarda, Rorbach, Joanna, Gao, Fei, Lewis, Richard J., Chrzanowska-Lightowlers, Zofia M., Lightowlers, Robert N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Portland Press Ltd. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5468982/
https://www.ncbi.nlm.nih.gov/pubmed/28512204
http://dx.doi.org/10.1042/BCJ20170256