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Site-specific azide-acetyllysine photochemistry on epigenetic readers for interactome profiling

Chemical modifications on DNA, RNA and histones are recognized by an array of ‘reader’ modules to regulate transcriptional programming and cell fate. However, identification of reader-specific interacting partners in a dynamic cellular environment remains a significant challenge. Herein, we report a...

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Detalles Bibliográficos
Autores principales: Sudhamalla, Babu, Dey, Debasis, Breski, Megan, Nguyen, Tiffany, Islam, Kabirul
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Royal Society of Chemistry 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5468995/
https://www.ncbi.nlm.nih.gov/pubmed/28626565
http://dx.doi.org/10.1039/c7sc00284j