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Heterologous expression of cytotoxic sesquiterpenoids from the medicinal mushroom Lignosus rhinocerotis in yeast

BACKGROUND: Genome mining facilitated by heterologous systems is an emerging approach to access the chemical diversity encoded in basidiomycete genomes. In this study, three sesquiterpene synthase genes, GME3634, GME3638, and GME9210, which were highly expressed in the sclerotium of the medicinal mu...

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Detalles Bibliográficos
Autores principales: Yap, Hui-Yeng Yeannie, Muria-Gonzalez, Mariano Jordi, Kong, Boon-Hong, Stubbs, Keith A., Tan, Chon-Seng, Ng, Szu-Ting, Tan, Nget-Hong, Solomon, Peter S., Fung, Shin-Yee, Chooi, Yit-Heng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5468996/
https://www.ncbi.nlm.nih.gov/pubmed/28606152
http://dx.doi.org/10.1186/s12934-017-0713-x