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Heterologous expression of cytotoxic sesquiterpenoids from the medicinal mushroom Lignosus rhinocerotis in yeast
BACKGROUND: Genome mining facilitated by heterologous systems is an emerging approach to access the chemical diversity encoded in basidiomycete genomes. In this study, three sesquiterpene synthase genes, GME3634, GME3638, and GME9210, which were highly expressed in the sclerotium of the medicinal mu...
Autores principales: | Yap, Hui-Yeng Yeannie, Muria-Gonzalez, Mariano Jordi, Kong, Boon-Hong, Stubbs, Keith A., Tan, Chon-Seng, Ng, Szu-Ting, Tan, Nget-Hong, Solomon, Peter S., Fung, Shin-Yee, Chooi, Yit-Heng |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5468996/ https://www.ncbi.nlm.nih.gov/pubmed/28606152 http://dx.doi.org/10.1186/s12934-017-0713-x |
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