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MicroRNA-1296 inhibits metastasis and epithelial-mesenchymal transition of hepatocellular carcinoma by targeting SRPK1-mediated PI3K/AKT pathway

BACKGROUND: Increasing evidences demonstrate that miRNAs contribute to development and progression of hepatocellular carcinoma (HCC). Underexpression of miR-1296 is recently reported to promote growth and metastasis of human cancers. However, the expression and role of miR-1296 in HCC remain unknown...

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Detalles Bibliográficos
Autores principales: Xu, Qiuran, Liu, Xin, Liu, Zhikui, Zhou, Zhenyu, Wang, Yufeng, Tu, Jianfeng, Li, Lijie, Bao, Hangxing, Yang, Liu, Tu, Kangsheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5469159/
https://www.ncbi.nlm.nih.gov/pubmed/28606154
http://dx.doi.org/10.1186/s12943-017-0675-y