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What is the impact of PCSK9 rs505151 and rs11591147 polymorphisms on serum lipids level and cardiovascular risk: a meta-analysis

BACKGROUND: PCSK9 rs505151 and rs11591147 polymorphisms are identified as gain- and loss-of-function mutations, respectively. The effects of these polymorphisms on serum lipid levels and cardiovascular risk remain to be elucidated. METHODS: In this meta-analysis, we explored the association of PCSK9...

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Detalles Bibliográficos
Autores principales: Qiu, Chengfeng, Zeng, Pingyu, Li, Xiaohui, Zhang, Zhen, Pan, Bingjie, Peng, Zhou Y. F., Li, Yapei, Ma, Yeshuo, Leng, Yiping, Chen, Ruifang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5469167/
https://www.ncbi.nlm.nih.gov/pubmed/28606094
http://dx.doi.org/10.1186/s12944-017-0506-6