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The evolutionary trade‐off between stem cell niche size, aging, and tumorigenesis
Many epithelial tissues within multicellular organisms are continually replenished by small independent populations of stem cells largely responsible for maintaining tissue homeostasis. These continually dividing populations are subject to mutations that can lead to tumorigenesis but also contribute...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5469181/ https://www.ncbi.nlm.nih.gov/pubmed/28616066 http://dx.doi.org/10.1111/eva.12476 |