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The evolutionary trade‐off between stem cell niche size, aging, and tumorigenesis

Many epithelial tissues within multicellular organisms are continually replenished by small independent populations of stem cells largely responsible for maintaining tissue homeostasis. These continually dividing populations are subject to mutations that can lead to tumorigenesis but also contribute...

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Detalles Bibliográficos
Autores principales: Cannataro, Vincent L., McKinley, Scott A., St. Mary, Colette M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5469181/
https://www.ncbi.nlm.nih.gov/pubmed/28616066
http://dx.doi.org/10.1111/eva.12476