Cargando…
The evolutionary trade‐off between stem cell niche size, aging, and tumorigenesis
Many epithelial tissues within multicellular organisms are continually replenished by small independent populations of stem cells largely responsible for maintaining tissue homeostasis. These continually dividing populations are subject to mutations that can lead to tumorigenesis but also contribute...
Autores principales: | Cannataro, Vincent L., McKinley, Scott A., St. Mary, Colette M. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2017
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5469181/ https://www.ncbi.nlm.nih.gov/pubmed/28616066 http://dx.doi.org/10.1111/eva.12476 |
Ejemplares similares
-
The implications of small stem cell niche sizes and the distribution of fitness effects of new mutations in aging and tumorigenesis
por: Cannataro, Vincent L., et al.
Publicado: (2016) -
Stress, genomic adaptation, and the evolutionary trade-off
por: Horne, Steven D., et al.
Publicado: (2014) -
The cultural evolutionary trade-off of ritualistic synchrony
por: Gelfand, Michele J., et al.
Publicado: (2020) -
Evolutionary trade-off in reproduction of Cambrian arthropods
por: Ou, Qiang, et al.
Publicado: (2020) -
Ancient Evolutionary Trade-Offs between Yeast Ploidy States
por: Zörgö, Enikö, et al.
Publicado: (2013)