Effects of local and spinal administrations of mu-opioids on postoperative pain in aged vs adult mice

INTRODUCTION: Suboptimal management of postoperative pain leads to increased risk of chronic opioid therapy, especially in elderly patients. OBJECTIVES: Although this age-dependent phenomenon has been observed clinically, basic mechanisms including baseline nociception, postoperative hypersensitivit...

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Detalles Bibliográficos
Autores principales: Mecklenburg, Jennifer, Patil, Mayur J., Koek, Wouter, Akopian, Armen N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wolters Kluwer 2017
Materias:
Basic Science
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5469295/
https://www.ncbi.nlm.nih.gov/pubmed/28626834
http://dx.doi.org/10.1097/PR9.0000000000000584

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5469295/
https://www.ncbi.nlm.nih.gov/pubmed/28626834
http://dx.doi.org/10.1097/PR9.0000000000000584

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