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A GPR119 Signaling System in the Murine Eye Regulates Intraocular Pressure in a Sex-Dependent Manner

PURPOSE: GPR119 is a G protein–coupled receptor that may be the endogenous target for 2-oleoylglycerol (2-OG), a lipid related to the endocannabinoid family of neuromodulators. Interest in GPR119 has centered on its role in regulating insulin secretion; however, the role of GPR119 has not been exami...

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Detalles Bibliográficos
Autores principales: Miller, Sally, Hu, Sherry Shu-Jung, Leishman, Emma, Morgan, Dan, Wager-Miller, Jim, Mackie, Ken, Bradshaw, Heather B., Straiker, Alex
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Association for Research in Vision and Ophthalmology 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5469424/
https://www.ncbi.nlm.nih.gov/pubmed/28593245
http://dx.doi.org/10.1167/iovs.16-21330