No evidence for genome editing in mouse zygotes and HEK293T human cell line using the DNA-guided Natronobacterium gregoryi Argonaute (NgAgo)

A recently published research article reported that the extreme halophile archaebacterium Natronobacterium gregoryi Argonaute enzyme (NgAgo) could cleave the cellular DNA under physiological temperature conditions in cell line and be implemented as an alternative to CRISPR/Cas9 genome editing techno...

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Detalles Bibliográficos
Autores principales: Khin, Nay Chi, Lowe, Jenna L., Jensen, Lora M., Burgio, Gaetan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5469460/
https://www.ncbi.nlm.nih.gov/pubmed/28609472
http://dx.doi.org/10.1371/journal.pone.0178768

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5469460/
https://www.ncbi.nlm.nih.gov/pubmed/28609472
http://dx.doi.org/10.1371/journal.pone.0178768

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