An investigation into the effects of excipient particle size, blending techniques and processing parameters on the homogeneity and content uniformity of a blend containing low-dose model drug

Powder blend homogeneity is a critical attribute in formulation development of low dose and potent active pharmaceutical ingredients (API) yet a complex process with multiple contributing factors. Excipient characteristics play key role in efficient blending process and final product quality. In thi...

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Detalles Bibliográficos
Autores principales: Alyami, Hamad, Dahmash, Eman, Bowen, James, Mohammed, Afzal R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5469472/
https://www.ncbi.nlm.nih.gov/pubmed/28609454
http://dx.doi.org/10.1371/journal.pone.0178772

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5469472/
https://www.ncbi.nlm.nih.gov/pubmed/28609454
http://dx.doi.org/10.1371/journal.pone.0178772

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