Cooperative inhibition of RIP1-mediated NF-κB signaling by cytomegalovirus-encoded deubiquitinase and inactive homolog of cellular ribonucleotide reductase large subunit

Several viruses have been found to encode a deubiquitinating protease (DUB). These viral DUBs are proposed to play a role in regulating innate immune or inflammatory signaling. In human cytomegalovirus (HCMV), the largest tegument protein encoded by UL48 contains DUB activity, but its cellular targe...

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Detalles Bibliográficos
Autores principales: Kwon, Ki Mun, Oh, Se Eun, Kim, Young Eui, Han, Tae-Hee, Ahn, Jin-Hyun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5469499/
https://www.ncbi.nlm.nih.gov/pubmed/28570668
http://dx.doi.org/10.1371/journal.ppat.1006423

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5469499/
https://www.ncbi.nlm.nih.gov/pubmed/28570668
http://dx.doi.org/10.1371/journal.ppat.1006423

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