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Regulation of lung endothelial permeability and inflammatory responses by prostaglandin A2: role of EP4 receptor

The role of prostaglandin A2 (PGA2) in modulation of vascular endothelial function is unknown. We investigated effects of PGA2 on pulmonary endothelial cell (EC) permeability and inflammatory activation and identified a receptor mediating these effects. PGA2 enhanced the EC barrier and protected aga...

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Detalles Bibliográficos
Autores principales: Ohmura, Tomomi, Tian, Yufeng, Sarich, Nicolene, Ke, Yunbo, Meliton, Angelo, Shah, Alok S., Andreasson, Katrin, Birukov, Konstantin G., Birukova, Anna A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society for Cell Biology 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5469606/
https://www.ncbi.nlm.nih.gov/pubmed/28428256
http://dx.doi.org/10.1091/mbc.E16-09-0639