Sortilin and retromer mediate retrograde transport of Glut4 in 3T3-L1 adipocytes

Sortilin is a multiligand sorting receptor responsible for the anterograde transport of lysosomal enzymes and substrates. Here we demonstrate that sortilin is also involved in retrograde protein traffic. In cultured 3T3-L1 adipocytes, sortilin together with retromer rescues Glut4 from degradation in...

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Detalles Bibliográficos
Autores principales: Pan, Xiang, Zaarur, Nava, Singh, Maneet, Morin, Peter, Kandror, Konstantin V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society for Cell Biology 2017
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5469609/
https://www.ncbi.nlm.nih.gov/pubmed/28450454
http://dx.doi.org/10.1091/mbc.E16-11-0777

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5469609/
https://www.ncbi.nlm.nih.gov/pubmed/28450454
http://dx.doi.org/10.1091/mbc.E16-11-0777

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