Cargando…

Microtubule dynamics drive enhanced chromatin motion and mobilize telomeres in response to DNA damage

Chromatin exhibits increased mobility on DNA damage, but the biophysical basis for this behavior remains unknown. To explore the mechanisms that drive DNA damage–induced chromosome mobility, we use single-particle tracking of tagged chromosomal loci during interphase in live yeast cells together wit...

Descripción completa

Detalles Bibliográficos
Autores principales: Lawrimore, Josh, Barry, Timothy M., Barry, Raymond M., York, Alyssa C., Friedman, Brandon, Cook, Diana M., Akialis, Kristen, Tyler, Jolien, Vasquez, Paula, Yeh, Elaine, Bloom, Kerry
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society for Cell Biology 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5469612/
https://www.ncbi.nlm.nih.gov/pubmed/28450453
http://dx.doi.org/10.1091/mbc.E16-12-0846