Cargando…
Microtubule dynamics drive enhanced chromatin motion and mobilize telomeres in response to DNA damage
Chromatin exhibits increased mobility on DNA damage, but the biophysical basis for this behavior remains unknown. To explore the mechanisms that drive DNA damage–induced chromosome mobility, we use single-particle tracking of tagged chromosomal loci during interphase in live yeast cells together wit...
Autores principales: | Lawrimore, Josh, Barry, Timothy M., Barry, Raymond M., York, Alyssa C., Friedman, Brandon, Cook, Diana M., Akialis, Kristen, Tyler, Jolien, Vasquez, Paula, Yeh, Elaine, Bloom, Kerry |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The American Society for Cell Biology
2017
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5469612/ https://www.ncbi.nlm.nih.gov/pubmed/28450453 http://dx.doi.org/10.1091/mbc.E16-12-0846 |
Ejemplares similares
-
Geometric partitioning of cohesin and condensin is a consequence of chromatin loops
por: Lawrimore, Josh, et al.
Publicado: (2018) -
Polymer models reveal how chromatin modification can modulate force at the kinetochore
por: Lawrimore, Josh, et al.
Publicado: (2022) -
Enrichment of dynamic chromosomal crosslinks drive phase separation of the nucleolus
por: Hult, Caitlin, et al.
Publicado: (2017) -
DNA damage reduces heterogeneity and coherence of chromatin motions
por: Locatelli, Maëlle, et al.
Publicado: (2022) -
ChromoShake: a chromosome dynamics simulator reveals that chromatin loops stiffen centromeric chromatin
por: Lawrimore, Josh, et al.
Publicado: (2016)