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Coupling neutron reflectivity with cell-free protein synthesis to probe membrane protein structure in supported bilayers

The structure of the p7 viroporin, an oligomeric membrane protein ion channel involved in the assembly and release of the hepatitis C virus, was determined from proteins expressed and inserted directly into supported model lipid membranes using cell-free protein expression. Cell-free protein express...

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Detalles Bibliográficos
Autores principales: Soranzo, Thomas, Martin, Donald K., Lenormand, Jean-Luc, Watkins, Erik B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5469739/
https://www.ncbi.nlm.nih.gov/pubmed/28611396
http://dx.doi.org/10.1038/s41598-017-03472-8