Arrestins contribute to amyloid beta-induced cell death via modulation of autophagy and the α7nAch receptor in SH-SY5Y cells

Amyloid β-protein (Aβ) is believed to contribute to the development of Alzheimer’s disease (AD). Here we showed that Aβ(25-35) rapidly caused activation of autophagy, subsequently leading to reduction of autophagy associated with cellular apoptosis. Further investigation revealed that the accumulati...

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Detalles Bibliográficos
Autores principales: Liu, Yi-qing, Jia, Meng-qi, Xie, Zhao-hong, Liu, Xiao-fei, Hui-Yang, Zheng, Xiao-lei, Yuan, Hui-qing, Bi, Jian-zhong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5469748/
https://www.ncbi.nlm.nih.gov/pubmed/28611418
http://dx.doi.org/10.1038/s41598-017-01798-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5469748/
https://www.ncbi.nlm.nih.gov/pubmed/28611418
http://dx.doi.org/10.1038/s41598-017-01798-x

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