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Arrestins contribute to amyloid beta-induced cell death via modulation of autophagy and the α7nAch receptor in SH-SY5Y cells
Amyloid β-protein (Aβ) is believed to contribute to the development of Alzheimer’s disease (AD). Here we showed that Aβ(25-35) rapidly caused activation of autophagy, subsequently leading to reduction of autophagy associated with cellular apoptosis. Further investigation revealed that the accumulati...
Autores principales: | Liu, Yi-qing, Jia, Meng-qi, Xie, Zhao-hong, Liu, Xiao-fei, Hui-Yang, Zheng, Xiao-lei, Yuan, Hui-qing, Bi, Jian-zhong |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5469748/ https://www.ncbi.nlm.nih.gov/pubmed/28611418 http://dx.doi.org/10.1038/s41598-017-01798-x |
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