Performance of four modern whole genome amplification methods for copy number variant detection in single cells

Whole genome amplification (WGA) has become an invaluable tool to perform copy number variation (CNV) detection in single, or a limited number of cells. Unfortunately, current WGA methods introduce representation bias that limits the detection of small CNVs. New WGA methods have been introduced that...

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Detalles Bibliográficos
Autores principales: Deleye, Lieselot, Tilleman, Laurentijn, Vander Plaetsen, Ann-Sophie, Cornelis, Senne, Deforce, Dieter, Van Nieuwerburgh, Filip
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5469777/
https://www.ncbi.nlm.nih.gov/pubmed/28611458
http://dx.doi.org/10.1038/s41598-017-03711-y

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5469777/
https://www.ncbi.nlm.nih.gov/pubmed/28611458
http://dx.doi.org/10.1038/s41598-017-03711-y

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