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Ohmyungsamycins promote antimicrobial responses through autophagy activation via AMP-activated protein kinase pathway

The induction of host cell autophagy by various autophagy inducers contributes to the antimicrobial host defense against Mycobacterium tuberculosis (Mtb), a major pathogenic strain that causes human tuberculosis. In this study, we present a role for the newly identified cyclic peptides ohmyungsamyci...

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Detalles Bibliográficos
Autores principales: Kim, Tae Sung, Shin, Yern-Hyerk, Lee, Hye-Mi, Kim, Jin Kyung, Choe, Jin Ho, Jang, Ji-Chan, Um, Soohyun, Jin, Hyo Sun, Komatsu, Masaaki, Cha, Guang-Ho, Chae, Han-Jung, Oh, Dong-Chan, Jo, Eun-Kyeong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5469788/
https://www.ncbi.nlm.nih.gov/pubmed/28611371
http://dx.doi.org/10.1038/s41598-017-03477-3