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JNK Activation Turns on LPS- and Gram-Negative Bacteria-Induced NADPH Oxidase-Dependent Suicidal NETosis
Neutrophils cast neutrophil extracellular traps (NETs) to ensnare microbial pathogens. Nevertheless, the molecular rheostats that regulate NETosis in response to bacteria are not clearly established. We hypothesized that stress-activated protein kinase or c-Jun N-terminal Kinase (SAPK/JNK) is a mole...
Autores principales: | Khan, Meraj A., Farahvash, Armin, Douda, David N., Licht, Johann-Christoph, Grasemann, Hartmut, Sweezey, Neil, Palaniyar, Nades |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5469795/ https://www.ncbi.nlm.nih.gov/pubmed/28611461 http://dx.doi.org/10.1038/s41598-017-03257-z |
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