The osteogenesis-promoting effects of alpha-lipoic acid against glucocorticoid-induced osteoporosis through the NOX4, NF-kappaB, JNK and PI3K/AKT pathways

Recently, accumulating evidence has indicated that glucocorticoid-induced osteoporosis (GIOP) is closely related to oxidative stress and apoptosis. Alpha-lipoic acid (LA), a naturally endogenous anti-oxidant, possesses anti-oxidative and anti-apoptosis activities, implicating LA as a therapeutic age...

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Detalles Bibliográficos
Autores principales: Lu, Shi-Yu, Wang, Chang-Yuan, Jin, Yue, Meng, Qiang, Liu, Qi, Liu, Zhi-hao, Liu, Ke-Xin, Sun, Hui-Jun, Liu, Mo-Zhen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5469800/
https://www.ncbi.nlm.nih.gov/pubmed/28611356
http://dx.doi.org/10.1038/s41598-017-03187-w

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5469800/
https://www.ncbi.nlm.nih.gov/pubmed/28611356
http://dx.doi.org/10.1038/s41598-017-03187-w

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