Targeted sequencing of both DNA strands barcoded and captured individually by RNA probes to identify genome-wide ultra-rare mutations

Next Generation Sequencing (NGS) has been widely implemented in biological research and has made a profound impact on patient care. One of the essential NGS applications is to identify disease-causing sequence variants, where high coverage and accuracy are needed. Here, we reported a novel NGS pipel...

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Detalles Bibliográficos
Autores principales: Wang, Qing, Wang, Xu, Tang, Pheobe S., O’leary, Grace M., Zhang, Ming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5469810/
https://www.ncbi.nlm.nih.gov/pubmed/28611392
http://dx.doi.org/10.1038/s41598-017-03448-8

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5469810/
https://www.ncbi.nlm.nih.gov/pubmed/28611392
http://dx.doi.org/10.1038/s41598-017-03448-8

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