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Identification of GXXXXG motif in Chrysophsin-1 and its implication in the design of analogs with cell-selective antimicrobial and anti-endotoxin activities

Marine fish antimicrobial peptide, chrysophsin-1 possesses versatile biological activities but its non-selective nature restricts its therapeutic possibilities. Often small alterations in structural motifs result in significant changes in the properties of concerned proteins/peptides. We have identi...

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Detalles Bibliográficos
Autores principales: Tripathi, Amit Kumar, Kumari, Tripti, Harioudh, Munesh Kumar, Yadav, Pranjal Kumar, Kathuria, Manoj, Shukla, P. K., Mitra, Kalyan, Ghosh, Jimut Kanti
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5469811/
https://www.ncbi.nlm.nih.gov/pubmed/28611397
http://dx.doi.org/10.1038/s41598-017-03576-1