Cargando…

Chronic low-dose exposure to a mixture of environmental endocrine disruptors induces microRNAs/isomiRs deregulation in mouse concomitant with intratesticular estradiol reduction

Humans are environmentally exposed not only to single endocrine-disrupting chemicals (EDCs) but to mixtures that affect their reproductive health. In reproductive tissues, microRNAs (miRNAs) are emerging as key targets of EDCs. Here, we analysed changes in the testis “miRNome” (and their biogenesis...

Descripción completa

Detalles Bibliográficos
Autores principales: Buñay, Julio, Larriba, Eduardo, Moreno, Ricardo D., del Mazo, Jesús
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5469815/
https://www.ncbi.nlm.nih.gov/pubmed/28611354
http://dx.doi.org/10.1038/s41598-017-02752-7