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Compromised Survival of Cerebellar Molecular Layer Interneurons Lacking GDNF Receptors GFRα1 or RET Impairs Normal Cerebellar Motor Learning

The role of neurotrophic factors as endogenous survival proteins for brain neurons remains contentious. In the cerebellum, the signals controlling survival of molecular layer interneurons (MLIs) are unknown, and direct evidence for the requirement of a full complement of MLIs for normal cerebellar f...

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Detalles Bibliográficos
Autores principales: Sergaki, Maria Christina, López-Ramos, Juan Carlos, Stagkourakis, Stefanos, Gruart, Agnès, Broberger, Christian, Delgado-García, José María, Ibáñez, Carlos F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5469938/
https://www.ncbi.nlm.nih.gov/pubmed/28591570
http://dx.doi.org/10.1016/j.celrep.2017.05.030