Combination Treatment with PPARγ Ligand and Its Specific Inhibitor GW9662 Downregulates BIS and 14-3-3 Gamma, Inhibiting Stem-Like Properties in Glioblastoma Cells

PPARγ is a nuclear receptor that regulates differentiation and proliferation and is highly expressed in many cancer cells. Its synthetic ligands, such as rosiglitazone and ciglitazone, and its inhibitor GW9662, were shown to induce cellular differentiation, inhibit proliferation, and lead to apoptos...

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Detalles Bibliográficos
Autor principal: Im, Chang-Nim
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5470001/
https://www.ncbi.nlm.nih.gov/pubmed/28642874
http://dx.doi.org/10.1155/2017/5832824

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5470001/
https://www.ncbi.nlm.nih.gov/pubmed/28642874
http://dx.doi.org/10.1155/2017/5832824

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