Cargando…

Proteases Revisited: Roles and Therapeutic Implications in Fibrosis

Proteases target many substrates, triggering changes in distinct biological processes correlated with cell migration, EMT/EndMT and fibrosis. Extracellular protease activity, demonstrated by secreted and membrane-bound protease forms, leads to ECM degradation, activation of other proteases (i.e., pr...

Descripción completa

Detalles Bibliográficos
Autores principales: Kryczka, Jakub, Boncela, Joanna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5470025/
https://www.ncbi.nlm.nih.gov/pubmed/28642633
http://dx.doi.org/10.1155/2017/2570154