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MCL Plays an Anti-Inflammatory Role in Mycobacterium tuberculosis-Induced Immune Response by Inhibiting NF-κB and NLRP3 Inflammasome Activation

Mycobacterium tuberculosis (Mtb) remains a significant menace to global health as it induces granulomatous lung lesions and systemic inflammatory responses during active tuberculosis (TB). Micheliolide (MCL), a sesquiterpene lactone, was recently reported to have a function of relieving LPS-induced...

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Detalles Bibliográficos
Autores principales: Zhang, Qingwen, Jiang, Xinru, He, Weigang, Wei, Kailin, Sun, Jinxia, Qin, Xiangyang, Zheng, Yuejuan, Jiang, Xin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5470027/
https://www.ncbi.nlm.nih.gov/pubmed/28642632
http://dx.doi.org/10.1155/2017/2432904