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Hypersensitivity of Vagal Pulmonary Afferents Induced by Tumor Necrosis Factor Alpha in Mice

Tumor necrosis factor alpha (TNFα), a pro-inflammatory cytokine, plays a significant role in the pathogenesis of allergic asthma. Inhalation of TNFα also induces airway hyperresponsiveness in healthy human subjects, and the underlying mechanism is not fully understood. A recent study reported that T...

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Detalles Bibliográficos
Autores principales: Lin, Ruei-Lung, Gu, Qihai, Lee, Lu-Yuan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5470033/
https://www.ncbi.nlm.nih.gov/pubmed/28659824
http://dx.doi.org/10.3389/fphys.2017.00411