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Increased Postnatal Cardiac Hyperplasia Precedes Cardiomyocyte Hypertrophy in a Model of Hypertrophic Cardiomyopathy

Rationale: Hypertrophic cardiomyopathy (HCM) occurs in ~0.5% of the population and is a leading cause of sudden cardiac death (SCD) in young adults. Cardiomyocyte hypertrophy has been the accepted mechanism for cardiac enlargement in HCM, but the early signaling responsible for initiating hypertroph...

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Detalles Bibliográficos
Autores principales: Farrell, Emily T., Grimes, Adrian C., de Lange, Willem J., Armstrong, Annie E., Ralphe, J. Carter
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5470088/
https://www.ncbi.nlm.nih.gov/pubmed/28659827
http://dx.doi.org/10.3389/fphys.2017.00414