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Defined and Scalable Differentiation of Human Oligodendrocyte Precursors from Pluripotent Stem Cells in a 3D Culture System

Oligodendrocyte precursor cells (OPCs) offer considerable potential for the treatment of demyelinating diseases and injuries of the CNS. However, generating large quantities of high-quality OPCs remains a substantial challenge that impedes their therapeutic application. Here, we show that OPCs can b...

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Detalles Bibliográficos
Autores principales: Rodrigues, Gonçalo M.C., Gaj, Thomas, Adil, Maroof M., Wahba, Joyce, Rao, Antara T., Lorbeer, Franziska K., Kulkarni, Rishi U., Diogo, Maria Margarida, Cabral, Joaquim M.S., Miller, Evan W., Hockemeyer, Dirk, Schaffer, David V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5470111/
https://www.ncbi.nlm.nih.gov/pubmed/28552605
http://dx.doi.org/10.1016/j.stemcr.2017.04.027