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l-Tyrosine Confers Residualizing Properties to a d-Amino Acid-Rich Residualizing Peptide for Radioiodination of Internalizing Antibodies

PURPOSE: The aims of the study were to develop and evaluate a novel residualizing peptide for labeling internalizing antibodies with (124)I to support clinical development using immuno-positron emission tomography (PET). METHODS: The anti-epidermal growth factor receptor antibody ch806 was radiolabe...

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Detalles Bibliográficos
Autores principales: Lee, Fook T., Burvenich, Ingrid J. G., Guo, Nancy, Kocovski, Pece, Tochon-Danguy, Henri, Ackermann, Uwe, O’Keefe, Graeme J., Gong, Sylvia, Rigopoulos, Angela, Liu, Zhanqi, Gan, Hui K., Scott, Andrew M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5470130/
https://www.ncbi.nlm.nih.gov/pubmed/27457521
http://dx.doi.org/10.1177/1536012116647535