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PET Study of Sphingosine-1-Phosphate Receptor 1 Expression in Response to Vascular Inflammation in a Rat Model of Carotid Injury

Sphingosine-1-phosphate receptor (S1PR) activation plays a key role in vascular inflammatory response. Here, we report in vivo validation of [(11)C]TZ3321, a potent S1PR1 radioligand, for imaging vascular inflammation in a rat model of carotid injury. The right common carotid artery of male adult Sp...

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Detalles Bibliográficos
Autores principales: Liu, Hui, Jin, Hongjun, Yue, Xuyi, Han, Junbin, Baum, Pamela, Abendschein, Dana R., Tu, Zhude
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5470136/
https://www.ncbi.nlm.nih.gov/pubmed/28654378
http://dx.doi.org/10.1177/1536012116689770