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Simulation of complex data structures for planning of studies with focus on biomarker comparison
BACKGROUND: There are a growing number of observational studies that do not only focus on single biomarkers for predicting an outcome event, but address questions in a multivariable setting. For example, when quantifying the added value of new biomarkers in addition to established risk factors, the...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5470184/ https://www.ncbi.nlm.nih.gov/pubmed/28610631 http://dx.doi.org/10.1186/s12874-017-0364-y |