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Simulation of complex data structures for planning of studies with focus on biomarker comparison

BACKGROUND: There are a growing number of observational studies that do not only focus on single biomarkers for predicting an outcome event, but address questions in a multivariable setting. For example, when quantifying the added value of new biomarkers in addition to established risk factors, the...

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Detalles Bibliográficos
Autores principales:	Schulz, Andreas, Zöller, Daniela, Nickels, Stefan, Beutel, Manfred E., Blettner, Maria, Wild, Philipp S., Binder, Harald
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2017
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5470184/ https://www.ncbi.nlm.nih.gov/pubmed/28610631 http://dx.doi.org/10.1186/s12874-017-0364-y

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